NON-INTEGRATED STEM CELL MODELS OF EARLY EMBRYO DEVELOPMENT

Concurrent Speaker(s)

• 

  Mo Ebrahimkhani, MD (he/him/his)

  Department of Pathology, Pittsburgh Liver Research Center, McGowan Institute for Regenerative Medicine
  University of Pittsburgh, USA
• 

  Yasuhiro Takashima, MD, PhD

  CiRA
  Kyoto University, Japan

Presenting Author(s)

• AA

  Auriana Arabpour

  Department of Molecular, Cell, and Developmental Biology
  University of California, Los Angeles, USA
• 

  Yung Su Kim, PhD

  Mechanical Engineering
  University of Michigan, Ann Arbor, USA
• 

  Madeleine Linneberg-Agerholm

  Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Denmark
• 

  Jin Zhang, PhD

  Basic Medical Sciences
  Zhejiang University, China

Embryo models formed from stem cells open a scientifically and ethically conducive path for embryology. Here, speakers will focus on ‘Non-Integrated Embryo Models’ that mimic only certain tissues of human embryo development, often lack extra-embryonic membranes, and manifest the ability to form connected embryonic tissues and organs.

Presentations:

• NAIVE HUMAN PSCS MODEL PRE- TO POST-IMPLANTATION DEVELOPMENT
  

  Concurrent Speaker: Yasuhiro Takashima, MD, PhD – Kyoto University
• PERI-GASTRULATION PATTERNING OF THE HUMAN EMBRYONIC DISC DOES NOT REQUIRE AN EPITHELIAL TO MESENCHYMAL TRANSITION
  

  Presenting Author: Auriana Arabpour – University of California, Los Angeles
• METABOLIC AND LIPIDOMIC REMODELLING INSTRUCT EARLY MAMMALIAN EMBRYO DEVELOPMENT
  

  Presenting Author: Jin Zhang, PhD – Zhejiang University
• REGULATIVE DEVELOPMENT IN THE PREIMPLANTATION EMBRYO: A ROLE FOR OCT4 IN PLASTICITY MAINTENANCE IN THE MOUSE PRIMITIVE ENDODERM
  

  Presenting Author: Madeleine Linneberg-Agerholm – Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW)
• SELF-ORGANIZED, PERI-GASTRULATION HUMAN EMBRYO MODEL WITH TRILAMINAR EMBRYONIC DISC-, AMNION-, AND YOLK SAC-LIKE STRUCTURES
  

  Presenting Author: Yung Su Kim, PhD – University of Michigan, Ann Arbor
• MODELING POST-IMPLANTATION HUMAN EMBRYOGENESIS TO YOLK SAC BLOOD EMERGENCE
  

  Concurrent Speaker: Mo R. Ebrahimkhani, MD (he/him/his) – University of Pittsburgh