MECHANOBIOLOGY OF STEM CELLS AND TISSUES

Concurrent Speaker(s)

• 

  Sirio Dupont, PhD (he/him/his)

  Department of Molecular Medicine
  University of Padova, Italy
• 

  Eugenia Piddini, PhD

  University of Bristol, UK

Presenting Author(s)

• 

  Giulia Savorè, MD

  Biotecnologie Molecolari e Scienze per la Salute
  University of Torino, Italy
• 

  Clementine Villeneuve, PhD

  Cell and Tissue Dynamics
  Max Planck Institute for Molecular Biomedicine, Germany
• 

  Pamela Wenzel, PhD (she/her/hers)

  Integrative Biology and Pharmacology
  University of Texas Health Science Center at Houston, United States
• 

  Qiaoling Zhu, PhD

  College of Life Science and Technology
  Tongji University, China

This session will examine how mechanical forces direct behaviors of stem cells and define physiological properties of their resident tissues. We will explore the molecular basis of force sensing and force generation, explore how forces are transduced into biochemical signals, and discuss how altered forces promote stem cell pathologies.

Presentations:

• A MITOCHONDRIAL MECHANOTRANSDUCTION SIGNALING PATHWAY COORDINATES CELL FATE DIFFERENTIATION IN RESPONSE TO FORCES
  

  Concurrent Speaker: Sirio Dupont, PhD (he/him/his) – University of Padova
• UNRAVELING THE INTERPLAY BETWEEN CARDIAC MECHANOBIOLOGY AND METABOLIC REGULATION IN STEM CELL MODELS
  

  Presenting Author: Giulia Savorè, MD – University of Torino
• FORCE INITIATES MITOCHONDRIAL REMODELING NECESSARY FOR HEMATOPOIETIC STEM CELL FATE
  

  Presenting Author: Pamela L. Wenzel, PhD (she/her/hers) – University of Texas Health Science Center at Houston
• PROCR+ CHONDROPROGENITORS SENSE MECHANICAL STIMULI TO GOVERN ARTICULAR CARTILAGE MAINTENANCE AND REGENERATION
  

  Presenting Author: Qiaoling Zhu, PhD – Tongji University
• TISSUE-SCALE MECHANICS CONTROL STEM CELL FATE AND POSITIONING DURING EPITHELIAL DEVELOPMENT
  

  Presenting Author: Clementine Villeneuve, PhD – Max Planck Institute for Molecular Biomedicine
• P53-MEDIATED STEM CELL COMPETITION: INSIGHTS INTO MECHANISMS OF CLONAL DOMINANCE
  

  Concurrent Speaker: Eugenia Piddini, PhD – University of Bristol