.jpg "Hannele Ruohola-Baker, PhD photo")
University of Washington, United States
Decoding regeneration using computer designed proteins. Ruohola-Baker laboratory, In collaboration with the Institute for Protein Design has recently developed a novel, computer AI-designed, protein-based approach to govern regeneration by signaling pathways and precise epigenetic regulation (Levy et al. Cell Rep. 2022; Moody et al. PNAS 2017; Edman et al. Cell 2024). These AI-designed Tie2 and FGFRc-splice variant specific super-agonists are highly functional in vascular protection and accelerate regeneration in many tissues in an unprecedented manner (Alghadeer et al. Dev Cell 2023; Hanson-Drury et al. Front Dent Med 2023; Edman et al. Cell 2024; Zhao et al. EMBO Rep. 2021; Divine et al. Science 2021; Ben-Sasson et al. Nature 2021; Cao et al. Nature 2022; Lutz et al. Science 2023).
FRONTIERS IN EPIGENETIC CONTROL FOR ENHANCED STEM CELL THERAPIES
Wednesday, July 10, 2024
4:00 PM – 5:30 PM CEST