Innovation Showcase
Human induced pluripotent stem cells (iPSCs) offer unprecedented opportunities for biomedical research, drug discovery, and regenerative medicine. However, to fully capitalize on the potential of iPSCs, it is necessary to culture and differentiate them under optimal conditions. Poor cell survival, cell stress, and accumulation of genetic abnormalities have been long-standing challenges. This presentation will introduce and discuss the discovery and application of CEPT, a four-part small molecule cocktail for cytoprotective and stress-free cell culture. CEPT represents a novel end-to-end solution for iPSCs and other sensitive cell types and can be utilized for routine cell passaging, cryopreservation/thawing, single-cell cloning, gene editing, and organoid formation. At this Innovation Showcase, Dr. Ilyas Singeç, who led the discovery of the CEPT cocktail at the National Institutes of Health (NIH) and is currently the Chief Scientific Officer for FUJIFILM Cellular Dynamics Inc., will discuss the scientific rationale and practical advantages of culturing iPSCs with this new and safer approach.