NOVEL APPROACHES TO PROGRAM AND PERTURB CELL FATE

Concurrent Speaker(s)

• 

  Filipe Pereira, PhD (he/him/his)

  Lund Stem Cell Center, Wallenberg Centre for Molecular Medicine
  Lund University, Sweden
• 

  Baris Tursun, PhD (he/him/his)

  Institute of Cell and Systems Biology of Animals
  University of Hamburg, Germany

Presenting Author(s)

• 

  Matias Autio, PhD

  Genome Institute of Singapore, A*Star & National University of Singapore, Singapore
• 

  Stepan Jerabek, PhD

  Pediatrics
  Columbia University, USA
• 

  Gal Keshet (Cleitman Blackstien)

  The Azrieli Center for Stem Cells and Genetic Research, Department of Genetics
  The Hebrew University of Jerusalem, Israel
• 

  Camila Vazquez Echegaray, PhD

  Department of Laboratory Medicine, Division of Molecular Medicine and Gene Therapy
  Lund University, Sweden

This session on new technologies is being harnessed to precisely engineer the identity of clinically valuable human cells. The cross-disciplinary selection of speakers spans the fields of cell fate engineering and emerging technologies aiming to manipulate cells with high efficiency and fidelity.

Presentations:

• A COMBINATORIAL TRANSCRIPTION FACTOR SCREENING PLATFORM FOR IMMUNE CELL REPROGRAMMING
  

  Concurrent Speaker: Filipe Pereira, PhD (he/him/his) – Lund University
• VALIDATED GENOMIC SAFE HARBOUR LOCI & LANDING-PAD CASSETTES ENABLE EASY INTEGRATION AND STABLE TRANSGENE EXPRESSION IN HUMAN PLURIPOTENT STEM CELLS AND DIFFERENTIATED PROGENY
  

  Presenting Author: Matias Ilmari Autio, PhD – Genome Institute of Singapore, A*Star & National University of Singapore
• BASE EDITING IN HUMAN EMBRYOS ENABLES KNOCKDOWN OF PCSK9 WITHOUT DETRIMENTAL CHROMOSOMAL CHANGES
  

  Presenting Author: Stepan Jerabek, PhD – Columbia University
• UNCOVERING REGULATORS OF DEGREES OF CELLULAR PLASTICITY BY DIRECT REPROGRAMMING
  

  Presenting Author: Camila Vazquez Echegaray, PhD – Lund University
• A CRISPR SCREEN COMBINED WITH SINGLE-CELL TRANSCRIPTOMICS IN HUMAN PLURIPOTENT STEM CELLS DEFINES THE HIERARCHY OF TRANSCRIPTION FACTORS GOVERNING PLURIPOTENCY AND DIFFERENTIATION
  

  Presenting Author: Gal Keshet (Cleitman Blackstien) – The Hebrew University of Jerusalem
• IDENTIFYING NOVEL FACTORS THAT AFFECT CELLULAR REPROGRAMMING BY USING THE GENETIC MODEL ORGANISM C. ELEGANS
  

  Concurrent Speaker: Baris Tursun, PhD (he/him/his) – University of Hamburg