Innovation Showcase
The human brain is a complex system, and neither traditional 2D tissue culture techniques nor animal models can fully recapitulate the complexity necessary for understanding neural pathologies. In contrast, cutting-edge culture models such as human neural organoids contain diverse tissue-specific cell types—progenitors, neurons, and glial cells—thereby offering enhanced physiological relevance. Here, we will introduce the STEMdiff™ neural organoid portfolio, which can generate unguided or guided neural organoids from human pluripotent stem cells (hPSCs) with high efficiency. We will showcase the generation of unguided cerebral organoids for modeling microcephaly and epilepsy, and how to generate guided spinal cord organoids for modeling Amyotrophic Lateral Sclerosis. This presentation will feature our latest state-of-the-art product: Human iPSC-Derived Midbrain Organoids, which are shipped fully differentiated and ready for immediate use. We will showcase the quality of these organoids and their use in a variety of applications, such as studying Parkinson's disease and neuroinflammation.