Science Spotlight
Organized by: Gregory Block, Histone Therapeutics
Our symposium, "Frontiers in Epigenomic Control for Enhanced Stem Cell Therapies," will explore the latest advancements and methodologies in the field. It will delve into the successes and challenges of manipulating the epigenome to direct stem cell fate and function. The session will highlight the progress being made engineering therapeutically relevant cells as well as discussing the utility of epigenomic functional screening to understand basic cell development mechanisms.
4:00 - 4:10 Isaac Gabriel, University College London, UK
Gregory Block, Histone Therapeutics, Canada
WELCOME AND OVERVIEW OF EPIGENETIC GENE EDITING IN STEM CELLS
4:10 - 4:25 Debattama Sen, Harvard University / Massachusetts General Hospital Center for Cancer Research, USA
EPIGENETICS OF T-CELL EXHAUSTION
4:25 - 4:40 Sara Che, Tune Therapeutics, USA
PRECISION EPIGENOME EDITING FOR GUIDED IPSC DIFFERENTIATION
4:40 - 4:55 Hannele Ruohola-Baker, University of Washington, USA
DECODING REGENERATION USING COMPUTER DESIGNED EPIBINDER PROTEINS
4:55 - 5:00 QUESTIONS AND ANSWERS
Panel Moderator:
Isaac Gabriel, University College London, UK
5:00 - 5:30 PANEL DISCUSSION: LESSONS FROM THE EDITORS, MAKING ENHANCED CELLS A REALITY
Panel Moderator:
Gregory Block, Histone Therapeutics, Canada
Panelists:
Lise Munsie, CCRM (Centre for Commercialization of Regenerative Medicine), Canada
Rowan Flynn, RoslinCT, Scotland
Sarah Dickerson, FUJIFILM, USA