Innovation Showcase
Unlocking the full potential of patient-derived and genetically modified human induced pluripotent stem cells (hiPSCs) for disease modeling requires precise differentiation protocols. Despite the availability of various protocols and kits, the technical intricacies of hiPSC differentiation often lead to inefficiencies and reproducibility challenges. We aim to address these hurdles by leveraging CellRaft® Technology, offering solutions for hiPSC differentiation workflows.
What you will learn:
- How to enhance efficiency in hiPSC differentiation
- How to automate the monitoring and isolation of neural progenitor cells (NPCs), ensuring high fidelity differentiation
- How to improve hematopoietic progenitor cell (HSC) differentiation, leading to enhanced colony survival and yield
- How to utilize technology to streamline differentiation by accurately purifying populations, increasing differentiation accuracy
Overall, our findings underscore the significance of automating manual steps in hiPSC differentiation, highlighting how image-based monitoring, phenotypic selection, and isolation can enhance efficiency and fidelity, thereby expediting the development of relevant disease models.