Innovation Showcase
Tumors comprise various cell types, with only a small portion being cancer stem cells (CSCs) driving malignancy. Identifying CSCs is challenging due to the lack of specific markers and suitable culture methods. Traditional systems favor non-tumorigenic cells, leading to CSC loss. Mouse models aid less malignant tumor cultures, but they're costly and induce changes. Direct isolation of patient-specific tumor cells in defined culture is preferred. PromoCell’s new culture system, the Primary Cancer Culture System, offers universal CSC isolation from patient samples or xenografts. It selectively supports malignant cell traits, preserving original tumor diversity. Unlike traditional media, it depletes benign cells, ensuring CSC enrichment. This system is universally applicable to various CSC types and tumor stages without reliance on uncertain markers. It avoids cytotoxic agents in animal-free environments and is cost-effective. It can enrich CSCs in established cell lines or deplete non-cancerous cells from primary cultures, aiding biomarker identification. Overall, the Primary Cancer Culture System offers a reliable and versatile method for CSC isolation and culture.