Exhibit Hall Theater

CRACKING THE CODE: ACCELERATED DIRECTED DIFFERENTIATION OF HIGH PURITY NEURONS AND NEURAL CREST DERIVATIVES FROM ANY HIPSC LINE

Anatomic Incorporated's rapid, directed differentiation platform facilitates the manufacture of high-purity sensory neurons, motor neurons, melanocytes, Schwann cell precursors, and spinal dorsal horn neurons from any human induced pluripotent stem cell (hiPSC) line within just 7 to 9 days. These breakthroughs in manufacturing efficiency are due to precision-engineered protocols that use exclusively growth factors and small molecules, without the need for transcription factor overexpression. This allows for the first time efficient, scaled-out manufacturing of any of our cell types from any pluripotent stem cell line, enabling donor-specific disease modeling. This technology is available in the form of differentiation kits, off-the-shelf human cells, or tailored differentiation services.

Our sensory neurons express druggable pain targets and functionally respond to key reference compounds, making them invaluable for pain pathway studies. Our motor neurons, invaluable for the study of ALS, demonstrate robust functionality in electrophysiological assays. Our melanocytes exhibit characteristic pigmentation and gene expression profiles, ideal for investigating skin disorders and cosmetic applications. Our Schwann cell precursors provide the only scalable model for peripheral myelination in conjunction with our neuronal cell types. And finally, our dorsal horn population provide the first-ever humanized in vitro model for central pain mechanisms, including central sensitization.